General Information of the Compound
Compound ID
CP0926224
Compound Name
N-[3-Dimethylamino-1-(2-naphthyl)propyl]-4-phenylbenzamide HCl
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Structure
Formula
C28H29ClN2O
Molecular Weight
445.006
Canonical SMILES
CN(C)CCC(NC(=O)c1ccc(-c2ccccc2)cc1)c1ccc2ccccc2c1.Cl
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InChI
InChI=1S/C28H28N2O.ClH/c1-30(2)19-18-27(26-17-14-22-10-6-7-11-25(22)20-26)29-28(31)24-15-12-23(13-16-24)21-8-4-3-5-9-21;/h3-17,20,27H,18-19H2,1-2H3,(H,29,31);1H
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InChIKey
YRCORYFYZSRLJO-UHFFFAOYSA-N
Physicochemical Property
logP
6.3514
Rotatable Bonds
7
Heavy Atom Count
32
Polar Areas
32.34
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45481615
ChEMBL ID
CHEMBL574527
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02463, Urotensin-2 receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
EC50 = 120.23 nM
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