General Information of the Compound
| Compound ID |
CP0926166
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| Compound Name |
N-(2,6-difluorophenyl)-3-(3-{2-[(5-{[2-(dimethylamino)ethyl]oxy}-2-methylphenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
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| Structure |
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| Formula |
C35H31F2N7O2
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| Molecular Weight |
619.676
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| Canonical SMILES |
Cc1ccc(OCCN(C)C)cc1Nc1nccc(-c2c(-c3cccc(C(=O)Nc4c(F)cccc4F)c3)nc3ccccn23)n1
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| InChI |
InChI=1S/C35H31F2N7O2/c1-22-13-14-25(46-19-18-43(2)3)21-29(22)40-35-38-16-15-28(39-35)33-31(41-30-12-4-5-17-44(30)33)23-8-6-9-24(20-23)34(45)42-32-26(36)10-7-11-27(32)37/h4-17,20-21H,18-19H2,1-3H3,(H,42,45)(H,38,39,40)
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| InChIKey |
LZYYNJHSXYSINQ-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01101, Insulin receptor
Protein ID: PT01104, Insulin-like growth factor 1 receptor