General Information of the Compound
Compound ID
CP0922087
Compound Name
(2E)-2-(1-{5-chloro-2-[(4-fluorobenzyl)oxy]phenyl}-3-methylbutylidene)hydrazinecarboximidamide
    Show/Hide
Structure
Formula
C19H22ClFN4O
Molecular Weight
376.863
Canonical SMILES
CC(C)C/C(=N\NC(=N)N)c1cc(Cl)ccc1OCc1ccc(F)cc1
    Show/Hide
InChI
InChI=1S/C19H22ClFN4O/c1-12(2)9-17(24-25-19(22)23)16-10-14(20)5-8-18(16)26-11-13-3-6-15(21)7-4-13/h3-8,10,12H,9,11H2,1-2H3,(H4,22,23,25)/b24-17+
    Show/Hide
InChIKey
FAEXFYFMKLSXBK-JJIBRWJFSA-N
Physicochemical Property
logP
4.29137
Rotatable Bonds
7
Heavy Atom Count
26
Polar Areas
83.49
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
3
Complexity
26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 16728646
ChEMBL ID
CHEMBL241477
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00903, C-C chemokine receptor type 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS