General Information of the Compound
| Compound ID |
CP0904020
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| Compound Name |
6-Benzyl-N-(quinolin-3-yl)-5,6,7,8-tetrahydro-2,6-naphthyridin-1-amine
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| Synonyms |
PMID26413912-Compound-80
Tetra-hydro-naphthyridine derivative 1
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| Structure |
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| Formula |
C24H22N4
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| Molecular Weight |
366.468
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| Canonical SMILES |
c1ccc(CN2CCc3c(ccnc3Nc3cnc4ccccc4c3)C2)cc1
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| InChI |
InChI=1S/C24H22N4/c1-2-6-18(7-3-1)16-28-13-11-22-20(17-28)10-12-25-24(22)27-21-14-19-8-4-5-9-23(19)26-15-21/h1-10,12,14-15H,11,13,16-17H2,(H,25,27)
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| InChIKey |
WVIVDSQVVHCZNX-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01099, Fatty-acid amide hydrolase 1
Protein ID: PT00961, Fatty-acid amide hydrolase 1
Clinical Information about the Compound
Drug 1 ( Tetra-hydro-naphthyridine derivative 1 )
| Drug Name | Tetra-hydro-naphthyridine derivative 1 | ||
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| Company | RENOVIS, INC. KELLY, Michael, G. KINCAID, John GOWLUGARI, Sumithra KAUB, Carl | ||