General Information of the Compound
Compound ID
CP0902630
Compound Name
3-(4-Chlorophenyl)-3-(2-methylaminoethyl)isochroman-1-one HCl
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Structure
Formula
C18H19Cl2NO2
Molecular Weight
352.261
Canonical SMILES
CNCCC1(c2ccc(Cl)cc2)Cc2ccccc2C(=O)O1.Cl
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InChI
InChI=1S/C18H18ClNO2.ClH/c1-20-11-10-18(14-6-8-15(19)9-7-14)12-13-4-2-3-5-16(13)17(21)22-18;/h2-9,20H,10-12H2,1H3;1H
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InChIKey
WCTIPZMGJSWXAU-UHFFFAOYSA-N
Physicochemical Property
logP
3.9797
Rotatable Bonds
4
Heavy Atom Count
23
Polar Areas
38.33
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
23

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 49799279
ChEMBL ID
CHEMBL1173239
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02463, Urotensin-2 receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
EC50 = 1949.84 nM
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