General Information of the Compound
Compound ID
CP0898976
Compound Name
1-(5-chloro-2-isobutoxybenzyl)-N-(4-((ethylamino)methyl)phenyl)-5-methyl-1H-pyrazole-3-carboxamide hydrochloride
    Show/Hide
Structure
Formula
C25H32Cl2N4O2
Molecular Weight
491.463
Canonical SMILES
CCNCc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)ccc3OCC(C)C)n2)cc1.Cl
    Show/Hide
InChI
InChI=1S/C25H31ClN4O2.ClH/c1-5-27-14-19-6-9-22(10-7-19)28-25(31)23-12-18(4)30(29-23)15-20-13-21(26)8-11-24(20)32-16-17(2)3;/h6-13,17,27H,5,14-16H2,1-4H3,(H,28,31);1H
    Show/Hide
InChIKey
LSFJUIDZJSGZLZ-UHFFFAOYSA-N
Physicochemical Property
logP
5.71162
Rotatable Bonds
10
Heavy Atom Count
33
Polar Areas
68.18
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 44568704
ChEMBL ID
CHEMBL523158
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01205, Prostaglandin E2 receptor EP1 subtype
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 7.943 nM
   TI
   LI
   LO
   TS