General Information of the Compound
Compound ID
CP0894828
Compound Name
c[Pro-Arg-Phe-Phe-Asn-Phe-Phe-DPro]
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Structure
Formula
C56H68N12O9
Molecular Weight
1053.235
Canonical SMILES
N=C(N)NCCC[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O
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InChI
InChI=1S/C56H68N12O9/c57-47(69)34-43-52(74)64-42(32-37-20-9-3-10-21-37)51(73)66-44(33-38-22-11-4-12-23-38)54(76)68-29-15-26-46(68)55(77)67-28-14-25-45(67)53(75)61-39(24-13-27-60-56(58)59)48(70)62-40(30-35-16-5-1-6-17-35)49(71)63-41(50(72)65-43)31-36-18-7-2-8-19-36/h1-12,16-23,39-46H,13-15,24-34H2,(H2,57,69)(H,61,75)(H,62,70)(H,63,71)(H,64,74)(H,65,72)(H,66,73)(H4,58,59,60)/t39-,40-,41-,42-,43-,44-,45-,46+/m0/s1
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InChIKey
NRLQKQCDACMYGN-BWNODLHQSA-N
Physicochemical Property
logP
0.00027
Rotatable Bonds
14
Heavy Atom Count
77
Polar Areas
320.21
Hydrogen Bond Donor Count
10
Hydrogen Bond Acceptor Count
10
Complexity
77

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 137654791
ChEMBL ID
CHEMBL4095539
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02450, Melanocortin receptor 3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Kd = 1905.46 nM
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Protein ID: PT01431, Melanocortin receptor 4
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Kd = 1949.84 nM
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