General Information of the Compound
Compound ID
CP0894246
Compound Name
N-[3-Dimethylamino-1-(4-methylphenyl)propyl]-4-(2-naphthyl)benzamide HCl
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Structure
Formula
C29H31ClN2O
Molecular Weight
459.033
Canonical SMILES
Cc1ccc(C(CCN(C)C)NC(=O)c2ccc(-c3ccc4ccccc4c3)cc2)cc1.Cl
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InChI
InChI=1S/C29H30N2O.ClH/c1-21-8-10-24(11-9-21)28(18-19-31(2)3)30-29(32)25-15-12-23(13-16-25)27-17-14-22-6-4-5-7-26(22)20-27;/h4-17,20,28H,18-19H2,1-3H3,(H,30,32);1H
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InChIKey
YPBPFOQXTXODRC-UHFFFAOYSA-N
Physicochemical Property
logP
6.65982
Rotatable Bonds
7
Heavy Atom Count
33
Polar Areas
32.34
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45482455
ChEMBL ID
CHEMBL575630
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02463, Urotensin-2 receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
EC50 = 812.83 nM
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