General Information of the Compound
Compound ID
CP0885374
Compound Name
N-[1-(4-Chlorophenyl)-3-dimethylaminopropyl]-3-(4-methoxyphenyl)benzamide HCl
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Structure
Formula
C25H28Cl2N2O2
Molecular Weight
459.417
Canonical SMILES
COc1ccc(-c2cccc(C(=O)NC(CCN(C)C)c3ccc(Cl)cc3)c2)cc1.Cl
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InChI
InChI=1S/C25H27ClN2O2.ClH/c1-28(2)16-15-24(19-7-11-22(26)12-8-19)27-25(29)21-6-4-5-20(17-21)18-9-13-23(30-3)14-10-18;/h4-14,17,24H,15-16H2,1-3H3,(H,27,29);1H
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InChIKey
DMBHWWWFMIWDLF-UHFFFAOYSA-N
Physicochemical Property
logP
5.8602
Rotatable Bonds
8
Heavy Atom Count
31
Polar Areas
41.57
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45482436
ChEMBL ID
CHEMBL574730
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02463, Urotensin-2 receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
EC50 = 575.44 nM
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