General Information of the Compound
Compound ID
CP0880305
Compound Name
7-(cyclopropylmethoxy)-5-methyl-3-(4-methylthiazol-2-yl)-4H-chromen-4-one
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Structure
Formula
C18H17NO3S
Molecular Weight
327.405
Canonical SMILES
Cc1csc(-c2coc3cc(OCC4CC4)cc(C)c3c2=O)n1
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InChI
InChI=1S/C18H17NO3S/c1-10-5-13(21-7-12-3-4-12)6-15-16(10)17(20)14(8-22-15)18-19-11(2)9-23-18/h5-6,8-9,12H,3-4,7H2,1-2H3
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InChIKey
BBJLQNUOHJUWAC-UHFFFAOYSA-N
Physicochemical Property
logP
4.32214
Rotatable Bonds
4
Heavy Atom Count
23
Polar Areas
52.33
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Complexity
23

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 76329262
ChEMBL ID
CHEMBL3133068
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 79.43 nM
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