General Information of the Compound
Compound ID
CP0868816
Compound Name
(2Z)-2-[(Thiophen-2-yl)methylidene]-[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one
    Show/Hide
Structure
Formula
C14H8N2OS2
Molecular Weight
284.365
Canonical SMILES
O=c1/c(=C/c2cccs2)sc2nc3ccccc3n12
    Show/Hide
InChI
InChI=1S/C14H8N2OS2/c17-13-12(8-9-4-3-7-18-9)19-14-15-10-5-1-2-6-11(10)16(13)14/h1-8H/b12-8-
    Show/Hide
InChIKey
OXLGCDQFQLKXIM-WQLSENKSSA-N
Physicochemical Property
logP
2.5184
Rotatable Bonds
1
Heavy Atom Count
19
Polar Areas
34.37
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Complexity
19

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 1949153
ChEMBL ID
CHEMBL2391016
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01953, Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
Ki >= 10000 nM
   TI
   LI
   LO
   TS