General Information of the Compound
Compound ID
CP0866065
Compound Name
(+)-R-Cyclohexylammonium 2-{4-[2-(N-Heptyl-N-(benzoxazol-2-yl)amino-ethyl)]phenoxy}-3-phenyl-propanoate
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Structure
Formula
C37H49N3O4
Molecular Weight
599.816
Canonical SMILES
CCCCCCCN(CCc1ccc(O[C@H](Cc2ccccc2)C(=O)O)cc1)c1nc2ccccc2o1.NC1CCCCC1
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InChI
InChI=1S/C31H36N2O4.C6H13N/c1-2-3-4-5-11-21-33(31-32-27-14-9-10-15-28(27)37-31)22-20-24-16-18-26(19-17-24)36-29(30(34)35)23-25-12-7-6-8-13-25;7-6-4-2-1-3-5-6/h6-10,12-19,29H,2-5,11,20-23H2,1H3,(H,34,35);6H,1-5,7H2/t29-;/m1./s1
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InChIKey
KQVYIGLKGUWHDO-XXIQNXCHSA-N
Physicochemical Property
logP
8.1998
Rotatable Bonds
15
Heavy Atom Count
44
Polar Areas
101.82
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
44

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 56945391
SID: 135647734
ChEMBL ID
CHEMBL2206305
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00910, Peroxisome proliferator-activated receptor alpha
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
EC50 = 1720 nM
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Protein ID: PT00915, Peroxisome proliferator-activated receptor gamma
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
EC50 = 2700 nM
   TI
   LI
   LO
   TS