General Information of the Compound
Compound ID
CP0862421
Compound Name
(3aS,5aS)-6-(5-fluoropyridin-3-yl)-3a,5a-dimethyl-1,2,3,3a,3b,4,5,5a,8,8a,8b,9,10,10a-tetradecahydrodicyclopenta[a,f]naphthalen-2-ol
    Show/Hide
Structure
Formula
C23H30FNO
Molecular Weight
355.497
Canonical SMILES
C[C@]12CC(O)CC1CC[C@@H]1[C@@H]2CC[C@]2(C)C(c3cncc(F)c3)=CC[C@@H]12
    Show/Hide
InChI
InChI=1S/C23H30FNO/c1-22-8-7-21-18(4-3-15-10-17(26)11-23(15,21)2)20(22)6-5-19(22)14-9-16(24)13-25-12-14/h5,9,12-13,15,17-18,20-21,26H,3-4,6-8,10-11H2,1-2H3/t15?,17?,18-,20-,21-,22+,23-/m0/s1
    Show/Hide
InChIKey
ODFCIEVQPDCQMI-JJWXIMJISA-N
Physicochemical Property
logP
5.2275
Rotatable Bonds
1
Heavy Atom Count
26
Polar Areas
33.12
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 68087402
ChEMBL ID
CHEMBL3941797
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01584, Steroid 17-alpha-hydroxylase/17,20 lyase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000263 NCI-H295R Homo sapiens (Human)  1
1
IC50 <= 15 nM
   TI
   LI
   LO
   TS