General Information of the Compound
Compound ID
CP0852928
Compound Name
8-amino-2-(3,4-dimethoxyphenyl)-N-(3-morpholinopropyl)imidazo[1,2-a]pyridine-6-carboxamide dihydrochloride
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Structure
Formula
C23H31Cl2N5O4
Molecular Weight
512.438
Canonical SMILES
COc1ccc(-c2cn3cc(C(=O)NCCCN4CCOCC4)cc(N)c3n2)cc1OC.Cl.Cl
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InChI
InChI=1S/C23H29N5O4.2ClH/c1-30-20-5-4-16(13-21(20)31-2)19-15-28-14-17(12-18(24)22(28)26-19)23(29)25-6-3-7-27-8-10-32-11-9-27;;/h4-5,12-15H,3,6-11,24H2,1-2H3,(H,25,29);2*1H
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InChIKey
JGRFTXHRKGHJQD-UHFFFAOYSA-N
Physicochemical Property
logP
2.8964
Rotatable Bonds
8
Heavy Atom Count
34
Polar Areas
103.35
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
8
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 145963081
ChEMBL ID
CHEMBL4129255
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS