General Information of the Compound
Compound ID
CP0846020
Compound Name
1-(2-(benzyloxy)-5-chlorobenzyl)-5-methyl-N-(4-(morpholinomethyl)phenyl)-1H-pyrazole-3-carboxamide hydrochloride
    Show/Hide
Structure
Formula
C30H32Cl2N4O3
Molecular Weight
567.517
Canonical SMILES
Cc1cc(C(=O)Nc2ccc(CN3CCOCC3)cc2)nn1Cc1cc(Cl)ccc1OCc1ccccc1.Cl
    Show/Hide
InChI
InChI=1S/C30H31ClN4O3.ClH/c1-22-17-28(30(36)32-27-10-7-23(8-11-27)19-34-13-15-37-16-14-34)33-35(22)20-25-18-26(31)9-12-29(25)38-21-24-5-3-2-4-6-24;/h2-12,17-18H,13-16,19-21H2,1H3,(H,32,36);1H
    Show/Hide
InChIKey
ZMESATZRVIMIKV-UHFFFAOYSA-N
Physicochemical Property
logP
5.97852
Rotatable Bonds
9
Heavy Atom Count
39
Polar Areas
68.62
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
39

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 44568303
ChEMBL ID
CHEMBL479591
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01205, Prostaglandin E2 receptor EP1 subtype
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
2
Ki = 79.43 nM
   TI
   LI
   LO
   TS