General Information of the Compound
Compound ID
CP0845341
Compound Name
3-(4-Chlorophenyl)-3-(2-dimethylaminoethyl)-6-methoxy-isochroman-1-one oxalate
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Structure
Formula
C22H24ClNO7
Molecular Weight
449.887
Canonical SMILES
COc1ccc2c(c1)CC(CCN(C)C)(c1ccc(Cl)cc1)OC2=O.O=C(O)C(=O)O
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InChI
InChI=1S/C20H22ClNO3.C2H2O4/c1-22(2)11-10-20(15-4-6-16(21)7-5-15)13-14-12-17(24-3)8-9-18(14)19(23)25-20;3-1(4)2(5)6/h4-9,12H,10-11,13H2,1-3H3;(H,3,4)(H,5,6)
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InChIKey
JUKOIBSIRWEKJF-UHFFFAOYSA-N
Physicochemical Property
logP
3.0643
Rotatable Bonds
5
Heavy Atom Count
31
Polar Areas
113.37
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 49799136
ChEMBL ID
CHEMBL1173725
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02463, Urotensin-2 receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
EC50 = 954.99 nM
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