General Information of the Compound
Compound ID
CP0827680
Compound Name
MMV1302090
    Show/Hide
Formula
C22H23N5S
Molecular Weight
389.528
Canonical SMILES
Cc1ccc(-c2cs/c(=N\c3cccnc3)n2CCCn2ccnc2)cc1C
    Show/Hide
InChI
InChI=1S/C22H23N5S/c1-17-6-7-19(13-18(17)2)21-15-28-22(25-20-5-3-8-23-14-20)27(21)11-4-10-26-12-9-24-16-26/h3,5-9,12-16H,4,10-11H2,1-2H3/b25-22-
    Show/Hide
InChIKey
MPCUQHIXOGXGKI-LVWGJNHUSA-N
Physicochemical Property
logP
4.74764
Rotatable Bonds
6
Heavy Atom Count
28
Polar Areas
48
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
6
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
ChEMBL ID
CHEMBL3195168
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06101, Latent membrane protein 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
AC50 = 46891 nM
   TI
   LI
   LO
   TS