General Information of the Compound
Compound ID
CP0703991
Compound Name
Lithium salt of 2-(2,4-dichloro-benzoylamino)-5-(2-pyridin-2-yl-ethoxy)-benzoate
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Structure
Formula
C21H15Cl2LiN2O4
Molecular Weight
437.208
Canonical SMILES
O=C(Nc1ccc(OCCc2ccccn2)cc1C(=O)[O-])c1ccc(Cl)cc1Cl.[Li+]
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InChI
InChI=1S/C21H16Cl2N2O4.Li/c22-13-4-6-16(18(23)11-13)20(26)25-19-7-5-15(12-17(19)21(27)28)29-10-8-14-3-1-2-9-24-14;/h1-7,9,11-12H,8,10H2,(H,25,26)(H,27,28);/q;+1/p-1
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InChIKey
NKJJWSMQZCOFRU-UHFFFAOYSA-M
Physicochemical Property
logP
0.6297
Rotatable Bonds
7
Heavy Atom Count
30
Polar Areas
91.35
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44345432
ChEMBL ID
CHEMBL420525
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00915, Peroxisome proliferator-activated receptor gamma
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000593 Caco-2/TC-7 Homo sapiens (Human)  1
1
EC50 = 3200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1500 nM