General Information of the Compound
Compound ID
CP0579644
Compound Name
2-amino-8-[2-[3-(4-methoxy-N-methylanilino)pyrrolidin-1-yl]ethyl]-4-(5-methylfuran-2-yl)pteridin-7-one
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Structure
Formula
C25H29N7O3
Molecular Weight
475.553
Canonical SMILES
COc1ccc(cc1)N(C)C1CCN(CCn2c3nc(N)nc(-c4ccc(C)o4)c3ncc2=O)C1
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InChI
InChI=1S/C25H29N7O3/c1-16-4-9-20(35-16)22-23-24(29-25(26)28-22)32(21(33)14-27-23)13-12-31-11-10-18(15-31)30(2)17-5-7-19(34-3)8-6-17/h4-9,14,18H,10-13,15H2,1-3H3,(H2,26,28,29)
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InChIKey
LNZWNAQCCDTWHH-UHFFFAOYSA-N
Physicochemical Property
logP
2.55642
Rotatable Bonds
7
Heavy Atom Count
35
Polar Areas
115.54
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
10
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 163215472
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 > 10000 nM
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