General Information of the Compound
Compound ID
CP0579642
Compound Name
2-amino-4-(5-methylfuran-2-yl)-8-(3-phenylpropyl)pteridin-7-one
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Structure
Formula
C20H19N5O2
Molecular Weight
361.405
Canonical SMILES
Cc1ccc(o1)-c1nc(N)nc2n(CCCc3ccccc3)c(=O)cnc12
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InChI
InChI=1S/C20H19N5O2/c1-13-9-10-15(27-13)17-18-19(24-20(21)23-17)25(16(26)12-22-18)11-5-8-14-6-3-2-4-7-14/h2-4,6-7,9-10,12H,5,8,11H2,1H3,(H2,21,23,24)
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InChIKey
CMWXSRYHPVUFTA-UHFFFAOYSA-N
Physicochemical Property
logP
2.96992
Rotatable Bonds
5
Heavy Atom Count
27
Polar Areas
99.83
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 163215458
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 712 nM
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