General Information of the Compound
Compound ID
CP0579537
Compound Name
1-benzhydryl-4-[4-(1,2,4-triazol-1-yl)butyl]piperazine
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Structure
Formula
C23H29N5
Molecular Weight
375.52
Canonical SMILES
C(CCn1cncn1)CN1CCN(CC1)C(c1ccccc1)c1ccccc1
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InChI
InChI=1S/C23H29N5/c1-3-9-21(10-4-1)23(22-11-5-2-6-12-22)27-17-15-26(16-18-27)13-7-8-14-28-20-24-19-25-28/h1-6,9-12,19-20,23H,7-8,13-18H2
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InChIKey
SMRZRKQKIZLRQY-UHFFFAOYSA-N
Physicochemical Property
logP
3.4655
Rotatable Bonds
8
Heavy Atom Count
28
Polar Areas
37.19
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 14986611
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01449, P2X purinoceptor 7
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000186 RPMI-8226 Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS