General Information of the Compound
Compound ID
CP0577455
Compound Name
methyl 3-[(4-phenylmethoxyphenyl)sulfamoyl]thiophene-2-carboxylate
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Structure
Formula
C19H17NO5S2
Molecular Weight
403.481
Canonical SMILES
COC(=O)c1sccc1S(=O)(=O)Nc1ccc(OCc2ccccc2)cc1
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InChI
InChI=1S/C19H17NO5S2/c1-24-19(21)18-17(11-12-26-18)27(22,23)20-15-7-9-16(10-8-15)25-13-14-5-3-2-4-6-14/h2-12,20H,13H2,1H3
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InChIKey
HONOBMZXQMENDV-UHFFFAOYSA-N
Physicochemical Property
logP
3.9145
Rotatable Bonds
7
Heavy Atom Count
27
Polar Areas
81.7
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 16832161
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00894, Androgen receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000141 LNCaP Homo sapiens (Human)  1
1
IC50 > 50000 nM
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