General Information of the Compound
Compound ID
CP0576801
Compound Name
2-amino-4-(5-methylfuran-2-yl)-8-[2-(4-phenylpiperidin-1-yl)ethyl]pteridin-7-one
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Structure
Formula
C24H26N6O2
Molecular Weight
430.512
Canonical SMILES
Cc1ccc(o1)-c1nc(N)nc2n(CCN3CCC(CC3)c3ccccc3)c(=O)cnc12
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InChI
InChI=1S/C24H26N6O2/c1-16-7-8-19(32-16)21-22-23(28-24(25)27-21)30(20(31)15-26-22)14-13-29-11-9-18(10-12-29)17-5-3-2-4-6-17/h2-8,15,18H,9-14H2,1H3,(H2,25,27,28)
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InChIKey
BZOLKXSFTMRASS-UHFFFAOYSA-N
Physicochemical Property
logP
3.21672
Rotatable Bonds
5
Heavy Atom Count
32
Polar Areas
103.07
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
8
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 163215459
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 387.8 nM
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