General Information of the Compound
Compound ID
CP0576110
Compound Name
6-[(4-chlorophenyl)-imidazol-1-ylmethyl]-4-[[1-(trifluoromethylsulfonyl)piperidin-4-yl]amino]-1H-quinolin-2-one
    Show/Hide
Structure
Formula
C25H23ClF3N5O3S
Molecular Weight
566.005
Canonical SMILES
FC(F)(F)S(=O)(=O)N1CCC(CC1)Nc1cc(=O)[nH]c2ccc(cc12)C(c1ccc(Cl)cc1)n1ccnc1
    Show/Hide
InChI
InChI=1S/C25H23ClF3N5O3S/c26-18-4-1-16(2-5-18)24(33-12-9-30-15-33)17-3-6-21-20(13-17)22(14-23(35)32-21)31-19-7-10-34(11-8-19)38(36,37)25(27,28)29/h1-6,9,12-15,19,24H,7-8,10-11H2,(H2,31,32,35)
    Show/Hide
InChIKey
YUEBYPWCNMZFOD-UHFFFAOYSA-N
Physicochemical Property
logP
4.7416
Rotatable Bonds
6
Heavy Atom Count
38
Polar Areas
100.09
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
38

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 145992799
ChEMBL ID
CHEMBL4284299
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01298, Cannabinoid receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 5 nM
   TI
   LI
   LO
   TS