General Information of the Compound
Compound ID
CP0575218
Compound Name
benzyl N-[(1S)-1-[(3S,7aR)-6-[3-(3-aminopropylamino)propyl]-5,7-dioxo-3,7a-dihydro-1H-imidazo[1,5-c][1,3]thiazol-3-yl]-3-methylbutyl]carbamate
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Structure
Formula
C24H37N5O4S
Molecular Weight
491.658
Canonical SMILES
CC(C)C[C@H](NC(=O)OCc1ccccc1)[C@@H]1SC[C@@H]2N1C(=O)N(CCCNCCCN)C2=O
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InChI
InChI=1S/C24H37N5O4S/c1-17(2)14-19(27-23(31)33-15-18-8-4-3-5-9-18)22-29-20(16-34-22)21(30)28(24(29)32)13-7-12-26-11-6-10-25/h3-5,8-9,17,19-20,22,26H,6-7,10-16,25H2,1-2H3,(H,27,31)/t19-,20-,22-/m0/s1
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InChIKey
JQJHURSEYIQCRT-ONTIZHBOSA-N
Physicochemical Property
logP
2.3617
Rotatable Bonds
13
Heavy Atom Count
34
Polar Areas
117
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
7
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 168280604
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01242, Polyunsaturated fatty acid 5-lipoxygenase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000831 PMNL Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS