General Information of the Compound
| Compound ID |
CP0575043
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| Compound Name |
6-[2-chloro-4-(3-methyl-2-oxopyridin-1-yl)phenyl]-N-(cyclopropylmethyl)-1H-indazole-3-carboxamide
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| Formula |
C24H21ClN4O2
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| Molecular Weight |
432.911
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| Canonical SMILES |
Cc1cccn(-c2ccc(c(Cl)c2)-c2ccc3c(n[nH]c3c2)C(=O)NCC2CC2)c1=O
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| InChI |
InChI=1S/C24H21ClN4O2/c1-14-3-2-10-29(24(14)31)17-7-9-18(20(25)12-17)16-6-8-19-21(11-16)27-28-22(19)23(30)26-13-15-4-5-15/h2-3,6-12,15H,4-5,13H2,1H3,(H,26,30)(H,27,28)
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| InChIKey |
SHZDYBRYBGENMG-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01042, Serine/threonine-protein kinase PAK 1
Protein ID: PT01317, Serine/threonine-protein kinase PAK 4