General Information of the Compound
Compound ID
CP0574262
Compound Name
2-[6-[(E)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]naphthalen-2-yl]oxy-N-(4-nitrophenyl)acetamide
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Structure
Formula
C22H15N3O6S
Molecular Weight
449.444
Canonical SMILES
[O-][N+](=O)c1ccc(NC(=O)COc2ccc3cc(\C=C4\SC(=O)NC4=O)ccc3c2)cc1
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InChI
InChI=1S/C22H15N3O6S/c26-20(23-16-4-6-17(7-5-16)25(29)30)12-31-18-8-3-14-9-13(1-2-15(14)11-18)10-19-21(27)24-22(28)32-19/h1-11H,12H2,(H,23,26)(H,24,27,28)/b19-10+
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InChIKey
CZWQVHMBWIVBNF-VXLYETTFSA-N
Physicochemical Property
logP
4.0894
Rotatable Bonds
6
Heavy Atom Count
32
Polar Areas
127.64
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
7
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 166631636
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00915, Peroxisome proliferator-activated receptor gamma
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
EC50 = 1610 nM
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