General Information of the Compound
Compound ID
CP0573904
Compound Name
1-(2,2-dimethylpropyl)-3-[1-[(4-phenylphenyl)methyl]-2,3-dihydroindol-5-yl]thiourea
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Structure
Formula
C27H31N3S
Molecular Weight
429.633
Canonical SMILES
CC(C)(C)CNC(=S)Nc1ccc2N(Cc3ccc(cc3)-c3ccccc3)CCc2c1
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InChI
InChI=1S/C27H31N3S/c1-27(2,3)19-28-26(31)29-24-13-14-25-23(17-24)15-16-30(25)18-20-9-11-22(12-10-20)21-7-5-4-6-8-21/h4-14,17H,15-16,18-19H2,1-3H3,(H2,28,29,31)
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InChIKey
VCDMFLZHZJGGNT-UHFFFAOYSA-N
Physicochemical Property
logP
6.2488
Rotatable Bonds
5
Heavy Atom Count
31
Polar Areas
27.3
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 168281011
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01242, Polyunsaturated fatty acid 5-lipoxygenase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000831 PMNL Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS