General Information of the Compound
Compound ID
CP0572911
Compound Name
benzyl N-[(1S)-1-[(3S,7aR)-6-[3-(diaminomethylideneamino)propyl]-5,7-dioxo-3,7a-dihydro-1H-imidazo[1,5-c][1,3]thiazol-3-yl]-3-methylbutyl]carbamate
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Structure
Formula
C22H32N6O4S
Molecular Weight
476.603
Canonical SMILES
CC(C)C[C@H](NC(=O)OCc1ccccc1)[C@@H]1SC[C@@H]2N1C(=O)N(CCCNC(N)=N)C2=O
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InChI
InChI=1S/C22H32N6O4S/c1-14(2)11-16(26-21(30)32-12-15-7-4-3-5-8-15)19-28-17(13-33-19)18(29)27(22(28)31)10-6-9-25-20(23)24/h3-5,7-8,14,16-17,19H,6,9-13H2,1-2H3,(H,26,30)(H4,23,24,25)/t16-,17-,19-/m0/s1
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InChIKey
OUOWHRBPNJRHJY-LNLFQRSKSA-N
Physicochemical Property
logP
1.90637
Rotatable Bonds
10
Heavy Atom Count
33
Polar Areas
140.85
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
6
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 168288777
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01242, Polyunsaturated fatty acid 5-lipoxygenase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000831 PMNL Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS