General Information of the Compound
Compound ID
CP0571288
Compound Name
2-(3-methoxyphenyl)ethyl (E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate
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Structure
Formula
C20H22O6
Molecular Weight
358.39
Canonical SMILES
COc1cccc(CCOC(=O)\C=C\c2cc(OC)c(O)c(OC)c2)c1
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InChI
InChI=1S/C20H22O6/c1-23-16-6-4-5-14(11-16)9-10-26-19(21)8-7-15-12-17(24-2)20(22)18(13-15)25-3/h4-8,11-13,22H,9-10H2,1-3H3/b8-7+
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InChIKey
XRGOLYJSUQAQHN-BQYQJAHWSA-N
Physicochemical Property
logP
3.2171
Rotatable Bonds
8
Heavy Atom Count
26
Polar Areas
74.22
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 166634760
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01242, Polyunsaturated fatty acid 5-lipoxygenase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000831 PMNL Homo sapiens (Human)  1
1
IC50 = 210 nM
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