General Information of the Compound
Compound ID
CP0571241
Compound Name
2-phenylethyl 3-(4-hydroxy-3,5-dimethoxyphenyl)propanoate
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Structure
Formula
C19H22O5
Molecular Weight
330.38
Canonical SMILES
COc1cc(CCC(=O)OCCc2ccccc2)cc(OC)c1O
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InChI
InChI=1S/C19H22O5/c1-22-16-12-15(13-17(23-2)19(16)21)8-9-18(20)24-11-10-14-6-4-3-5-7-14/h3-7,12-13,21H,8-11H2,1-2H3
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InChIKey
QNEGWOQZIIYNHP-UHFFFAOYSA-N
Physicochemical Property
logP
3.1279
Rotatable Bonds
8
Heavy Atom Count
24
Polar Areas
64.99
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 66702427
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01242, Polyunsaturated fatty acid 5-lipoxygenase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000831 PMNL Homo sapiens (Human)  1
1
IC50 = 590 nM
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