General Information of the Compound
Compound ID
CP0569871
Compound Name
propyl (E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate
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Structure
Formula
C14H18O5
Molecular Weight
266.293
Canonical SMILES
CCCOC(=O)\C=C\c1cc(OC)c(O)c(OC)c1
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InChI
InChI=1S/C14H18O5/c1-4-7-19-13(15)6-5-10-8-11(17-2)14(16)12(9-10)18-3/h5-6,8-9,16H,4,7H2,1-3H3/b6-5+
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InChIKey
NNWZNWDZXFTCCH-AATRIKPKSA-N
Physicochemical Property
logP
2.3758
Rotatable Bonds
6
Heavy Atom Count
19
Polar Areas
64.99
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
19

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 59906308
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01242, Polyunsaturated fatty acid 5-lipoxygenase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000831 PMNL Homo sapiens (Human)  1
1
IC50 = 710 nM
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