General Information of the Compound
Compound ID
CP0568972
Compound Name
2-chloro-N-[3-(5-ethyl-1,3-benzoxazol-2-yl)phenyl]-5-nitrobenzamide
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Structure
Formula
C22H16ClN3O4
Molecular Weight
421.84
Canonical SMILES
CCc1ccc2oc(nc2c1)-c1cccc(NC(=O)c2cc(ccc2Cl)[N+]([O-])=O)c1
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InChI
InChI=1S/C22H16ClN3O4/c1-2-13-6-9-20-19(10-13)25-22(30-20)14-4-3-5-15(11-14)24-21(27)17-12-16(26(28)29)7-8-18(17)23/h3-12H,2H2,1H3,(H,24,27)
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InChIKey
QQKBNZFZFOSTFD-UHFFFAOYSA-N
Physicochemical Property
logP
5.8711
Rotatable Bonds
5
Heavy Atom Count
30
Polar Areas
98.27
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 1365274
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00915, Peroxisome proliferator-activated receptor gamma
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001062 RT112/84-FABP4 Homo sapiens (Human)  1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 54 nM