General Information of the Compound
Compound ID
CP0567301
Compound Name
3-(1-benzylpiperidin-4-yl)-1-(1H-indol-5-yl)propan-1-one
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Structure
Formula
C23H26N2O
Molecular Weight
346.474
Canonical SMILES
O=C(CCC1CCN(Cc2ccccc2)CC1)c1ccc2[nH]ccc2c1
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InChI
InChI=1S/C23H26N2O/c26-23(21-7-8-22-20(16-21)10-13-24-22)9-6-18-11-14-25(15-12-18)17-19-4-2-1-3-5-19/h1-5,7-8,10,13,16,18,24H,6,9,11-12,14-15,17H2
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InChIKey
CPQKZLNBCUOHCW-UHFFFAOYSA-N
Physicochemical Property
logP
5.043
Rotatable Bonds
6
Heavy Atom Count
26
Polar Areas
36.1
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 9924349
SID: 14896104
ChEMBL ID
CHEMBL4585990
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01509, Sigma non-opioid intracellular receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
Ki = 3.3 nM
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   LI
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