General Information of the Compound
Compound ID
CP0565132
Compound Name
3-chloro-2-(2-chloroethoxy)-5-[2-[4-[(4-methyl-2-methylsulfanyl-1,3-oxazol-5-yl)methoxy]phenyl]propan-2-yl]benzonitrile
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Structure
Formula
C24H24Cl2N2O3S
Molecular Weight
491.44
Canonical SMILES
CSc1nc(C)c(COc2ccc(cc2)C(C)(C)c2cc(Cl)c(OCCCl)c(c2)C#N)o1
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InChI
InChI=1S/C24H24Cl2N2O3S/c1-15-21(31-23(28-15)32-4)14-30-19-7-5-17(6-8-19)24(2,3)18-11-16(13-27)22(20(26)12-18)29-10-9-25/h5-8,11-12H,9-10,14H2,1-4H3
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InChIKey
HPDVKFBBNOPEBU-UHFFFAOYSA-N
Physicochemical Property
logP
6.7525
Rotatable Bonds
9
Heavy Atom Count
32
Polar Areas
68.28
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
6
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 146521696
ChEMBL ID
CHEMBL4761191
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00894, Androgen receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000141 LNCaP Homo sapiens (Human)  1
1
IC50 < 500 nM
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