General Information of the Compound
Compound ID
CP0564248
Compound Name
N-[(2R)-1-[(1-cyanocyclopropyl)amino]-1-oxo-3-(4-pyridin-2-ylpiperazin-1-yl)sulfonylpropan-2-yl]-3,3-dimethylbutanamide
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Formula
C22H32N6O4S
Molecular Weight
476.603
Canonical SMILES
CC(C)(C)CC(=O)N[C@@H](CS(=O)(=O)N1CCN(CC1)c1ccccn1)C(=O)NC1(CC1)C#N
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InChI
InChI=1S/C22H32N6O4S/c1-21(2,3)14-19(29)25-17(20(30)26-22(16-23)7-8-22)15-33(31,32)28-12-10-27(11-13-28)18-6-4-5-9-24-18/h4-6,9,17H,7-8,10-15H2,1-3H3,(H,25,29)(H,26,30)/t17-/m0/s1
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InChIKey
SJKOGFYCCHOYII-KRWDZBQOSA-N
Physicochemical Property
logP
0.62678
Rotatable Bonds
8
Heavy Atom Count
33
Polar Areas
135.5
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
7
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL4777335