General Information of the Compound
Compound ID
CP0562825
Compound Name
2-(tert-butylamino)-1-[5-[(4-fluorophenyl)methylamino]-2,3-dihydroindol-1-yl]ethanone
    Show/Hide
Structure
Formula
C21H26FN3O
Molecular Weight
355.457
Canonical SMILES
CC(C)(C)NCC(=O)N1CCc2cc(NCc3ccc(F)cc3)ccc12
    Show/Hide
InChI
InChI=1S/C21H26FN3O/c1-21(2,3)24-14-20(26)25-11-10-16-12-18(8-9-19(16)25)23-13-15-4-6-17(22)7-5-15/h4-9,12,23-24H,10-11,13-14H2,1-3H3
    Show/Hide
InChIKey
LEFPDFZTPWRJEV-UHFFFAOYSA-N
Physicochemical Property
logP
3.715
Rotatable Bonds
5
Heavy Atom Count
26
Polar Areas
44.37
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 168287917
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01242, Polyunsaturated fatty acid 5-lipoxygenase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000831 PMNL Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS