General Information of the Compound
Compound ID
CP0562578
Compound Name
N-[[2-fluoro-4-[5-(1-prop-2-enoyl-3,6-dihydro-2H-pyridin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]phenyl]methyl]benzamide
    Show/Hide
Structure
Formula
C28H24FN5O2
Molecular Weight
481.531
Canonical SMILES
Fc1cc(ccc1CNC(=O)c1ccccc1)-c1ncnc2[nH]cc(C3=CCN(CC3)C(=O)C=C)c12
    Show/Hide
InChI
InChI=1S/C28H24FN5O2/c1-2-24(35)34-12-10-18(11-13-34)22-16-30-27-25(22)26(32-17-33-27)20-8-9-21(23(29)14-20)15-31-28(36)19-6-4-3-5-7-19/h2-10,14,16-17H,1,11-13,15H2,(H,31,36)(H,30,32,33)
    Show/Hide
InChIKey
MLZFQUIEECNEMP-UHFFFAOYSA-N
Physicochemical Property
logP
4.4957
Rotatable Bonds
6
Heavy Atom Count
36
Polar Areas
90.98
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 164887528