General Information of the Compound
Compound ID
CP0558175
Compound Name
CHEMBL4439493
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Formula
C26H26N2O5
Molecular Weight
446.503
Canonical SMILES
CCC(CC)C1N(C(=O)C(O)=C1C(=O)c1ccc(OC)cc1)c1ccc(cc1)-c1ccon1
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InChI
InChI=1S/C26H26N2O5/c1-4-16(5-2)23-22(24(29)18-8-12-20(32-3)13-9-18)25(30)26(31)28(23)19-10-6-17(7-11-19)21-14-15-33-27-21/h6-16,23,30H,4-5H2,1-3H3
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InChIKey
OSYJTEVIPYRGNR-UHFFFAOYSA-N
Physicochemical Property
logP
5.1966
Rotatable Bonds
8
Heavy Atom Count
33
Polar Areas
92.87
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
SID: 56416825
ChEMBL ID
CHEMBL4439493
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03393, P2X purinoceptor 3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000093 C6-BU-1 Rattus norvegicus (Rat)  1
1
IC50 = 10 nM
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