General Information of the Compound
Compound ID
CP0555690
Compound Name
1-[1-[5-(3-chloro-4-propan-2-yloxyphenyl)-1,3,4-thiadiazol-2-yl]piperidin-4-yl]piperidine-3-carboxylic acid
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Structure
Formula
C22H29ClN4O3S
Molecular Weight
465.019
Canonical SMILES
CC(C)Oc1ccc(cc1Cl)-c1nnc(s1)N1CCC(CC1)N1CCCC(C1)C(O)=O
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InChI
InChI=1S/C22H29ClN4O3S/c1-14(2)30-19-6-5-15(12-18(19)23)20-24-25-22(31-20)26-10-7-17(8-11-26)27-9-3-4-16(13-27)21(28)29/h5-6,12,14,16-17H,3-4,7-11,13H2,1-2H3,(H,28,29)
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InChIKey
UGWHSEANSHAVLP-UHFFFAOYSA-N
Physicochemical Property
logP
4.4111
Rotatable Bonds
6
Heavy Atom Count
31
Polar Areas
78.79
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 127028149
ChEMBL ID
CHEMBL3771026
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01688, Sphingosine 1-phosphate receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000466 McA-RH7777 Rattus norvegicus (Rat)  1
1
EC50 = 3981.07 nM
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