General Information of the Compound
Compound ID
CP0555162
Compound Name
CHEMBL4544543
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Formula
C28H22N2O6
Molecular Weight
482.492
Canonical SMILES
COc1ccc(cc1)C(=O)C1=C(O)C(=O)N(C1c1ccccc1OC)c1ccc(cc1)-c1ccon1
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InChI
InChI=1S/C28H22N2O6/c1-34-20-13-9-18(10-14-20)26(31)24-25(21-5-3-4-6-23(21)35-2)30(28(33)27(24)32)19-11-7-17(8-12-19)22-15-16-36-29-22/h3-16,25,32H,1-2H3
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InChIKey
DUOBRJOSFTXCLL-UHFFFAOYSA-N
Physicochemical Property
logP
5.1417
Rotatable Bonds
7
Heavy Atom Count
36
Polar Areas
102.1
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
SID: 56417080
ChEMBL ID
CHEMBL4544543
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03393, P2X purinoceptor 3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000093 C6-BU-1 Rattus norvegicus (Rat)  1
1
IC50 = 140 nM
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