General Information of the Compound
Compound ID
CP0548896
Compound Name
N-[2-(dimethylamino)ethyl]-1-ethyl-5-[3-[4-(3-ethyl-3-hydroxypentoxy)-3-methylphenyl]pentan-3-yl]pyrrole-2-carboxamide
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Structure
Formula
C30H49N3O3
Molecular Weight
499.74
Canonical SMILES
CCn1c(ccc1C(CC)(CC)c1ccc(OCCC(O)(CC)CC)c(C)c1)C(=O)NCCN(C)C
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InChI
InChI=1S/C30H49N3O3/c1-9-29(35,10-2)18-21-36-26-16-14-24(22-23(26)6)30(11-3,12-4)27-17-15-25(33(27)13-5)28(34)31-19-20-32(7)8/h14-17,22,35H,9-13,18-21H2,1-8H3,(H,31,34)
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InChIKey
RTEGDIBLJLIZTC-UHFFFAOYSA-N
Physicochemical Property
logP
5.53392
Rotatable Bonds
15
Heavy Atom Count
36
Polar Areas
66.73
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 137641740
ChEMBL ID
CHEMBL4085890
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02378, Vitamin D3 receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000018 HL-60 Homo sapiens (Human)  1
1
EC50 = 82 nM
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