General Information of the Compound
Compound ID
CP0546759
Compound Name
ethyl 4-[4-methoxy-3-(4-methoxybenzoyl)-5-oxo-2-phenyl-2H-pyrrol-1-yl]benzoate
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Structure
Formula
C28H25NO6
Molecular Weight
471.509
Canonical SMILES
CCOC(=O)c1ccc(cc1)N1C(C(C(=O)c2ccc(OC)cc2)=C(OC)C1=O)c1ccccc1
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InChI
InChI=1S/C28H25NO6/c1-4-35-28(32)20-10-14-21(15-11-20)29-24(18-8-6-5-7-9-18)23(26(34-3)27(29)31)25(30)19-12-16-22(33-2)17-13-19/h5-17,24H,4H2,1-3H3
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InChIKey
SFQAMBUHVUOILN-UHFFFAOYSA-N
Physicochemical Property
logP
4.7432
Rotatable Bonds
8
Heavy Atom Count
35
Polar Areas
82.14
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
6
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 145953319
ChEMBL ID
CHEMBL4129448
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03393, P2X purinoceptor 3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000093 C6-BU-1 Rattus norvegicus (Rat)  1
1
IC50 = 9800 nM
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