General Information of the Compound
Compound ID
CP0545863
Compound Name
3-[3-[benzyl(methyl)amino]propyl]-5-phenyl-5,6-dihydrocyclopenta[f][1,3]benzoxazole-2,7-dione
    Show/Hide
Structure
Formula
C27H26N2O3
Molecular Weight
426.516
Canonical SMILES
CN(CCCn1c2cc3C(CC(=O)c3cc2oc1=O)c1ccccc1)Cc1ccccc1
    Show/Hide
InChI
InChI=1S/C27H26N2O3/c1-28(18-19-9-4-2-5-10-19)13-8-14-29-24-15-22-21(20-11-6-3-7-12-20)16-25(30)23(22)17-26(24)32-27(29)31/h2-7,9-12,15,17,21H,8,13-14,16,18H2,1H3
    Show/Hide
InChIKey
SRRZCSAXSHSITO-UHFFFAOYSA-N
Physicochemical Property
logP
4.8349
Rotatable Bonds
7
Heavy Atom Count
32
Polar Areas
55.45
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 118724301
ChEMBL ID
CHEMBL3360559
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01509, Sigma non-opioid intracellular receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
Ki = 72 nM
   TI
   LI
   LO
   TS