General Information of the Compound
Compound ID
CP0543405
Compound Name
2-[3-(hydroxymethyl)-4-[8-[(5-methyl-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-2-yl)amino]imidazo[1,2-b]pyridazin-6-yl]pyridin-2-yl]-3,4,6,7,8,9-hexahydropyrazino[1,2-a]indol-1-one
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Structure
Formula
C30H32N10O2
Molecular Weight
564.654
Canonical SMILES
CN1CCn2nc(Nc3cc(nn4ccnc34)-c3ccnc(N4CCn5c6CCCCc6cc5C4=O)c3CO)cc2C1
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InChI
InChI=1S/C30H32N10O2/c1-36-10-13-39-20(17-36)15-27(35-39)33-24-16-23(34-40-9-8-32-29(24)40)21-6-7-31-28(22(21)18-41)38-12-11-37-25-5-3-2-4-19(25)14-26(37)30(38)42/h6-9,14-16,41H,2-5,10-13,17-18H2,1H3,(H,33,35)
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InChIKey
XCTHZVUJRUQEGV-UHFFFAOYSA-N
Physicochemical Property
logP
3.0098
Rotatable Bonds
5
Heavy Atom Count
42
Polar Areas
121.64
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
11
Complexity
42

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 71557629
SID: 163557688