General Information of the Compound
Compound ID
CP0543198
Compound Name
N-[3-[6-(3-pyrrolidin-1-ylpropoxy)-1,3-benzoxazol-2-yl]phenyl]benzamide
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Structure
Formula
C27H27N3O3
Molecular Weight
441.531
Canonical SMILES
O=C(Nc1cccc(c1)-c1nc2ccc(OCCCN3CCCC3)cc2o1)c1ccccc1
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InChI
InChI=1S/C27H27N3O3/c31-26(20-8-2-1-3-9-20)28-22-11-6-10-21(18-22)27-29-24-13-12-23(19-25(24)33-27)32-17-7-16-30-14-4-5-15-30/h1-3,6,8-13,18-19H,4-5,7,14-17H2,(H,28,31)
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InChIKey
JHCQRKZKHTWQQT-UHFFFAOYSA-N
Physicochemical Property
logP
5.6118
Rotatable Bonds
8
Heavy Atom Count
33
Polar Areas
67.6
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 137653682
ChEMBL ID
CHEMBL4091970
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01922, Toll-like receptor 9
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 2560 nM
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