General Information of the Compound
Compound ID
CP0541656
Compound Name
6-Furan-2-yl-9-(3-phenyl-propyl)-9H-purin-2-ylamine
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Structure
Formula
C18H17N5O
Molecular Weight
319.368
Canonical SMILES
Nc1nc(-c2ccco2)c2ncn(CCCc3ccccc3)c2n1
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InChI
InChI=1S/C18H17N5O/c19-18-21-15(14-9-5-11-24-14)16-17(22-18)23(12-20-16)10-4-8-13-6-2-1-3-7-13/h1-3,5-7,9,11-12H,4,8,10H2,(H2,19,21,22)
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InChIKey
KUBCULDZDHDDSR-UHFFFAOYSA-N
Physicochemical Property
logP
3.3013
Rotatable Bonds
5
Heavy Atom Count
24
Polar Areas
82.76
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 9858219
SID: 14821404
ChEMBL ID
CHEMBL193761
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 6.8 nM
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