General Information of the Compound
Compound ID
CP0541104
Compound Name
(3S,3'R,4'S,5'S,6'R)-5-[(4-ethylphenyl)methyl]-6'-methylspiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol
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Structure
Formula
C22H26O5
Molecular Weight
370.445
Canonical SMILES
CCc1ccc(Cc2ccc3CO[C@]4(O[C@H](C)[C@@H](O)[C@H](O)[C@H]4O)c3c2)cc1
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InChI
InChI=1S/C22H26O5/c1-3-14-4-6-15(7-5-14)10-16-8-9-17-12-26-22(18(17)11-16)21(25)20(24)19(23)13(2)27-22/h4-9,11,13,19-21,23-25H,3,10,12H2,1-2H3/t13-,19-,20+,21-,22+/m1/s1
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InChIKey
TYKNXFPQGLILIT-YKQWKKEUSA-N
Physicochemical Property
logP
2.0242
Rotatable Bonds
3
Heavy Atom Count
27
Polar Areas
79.15
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
5
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 135360458
ChEMBL ID
CHEMBL4515335
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03804, Sodium/glucose cotransporter 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 22300 nM
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Protein ID: PT02415, Sodium/glucose cotransporter 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 63.5 nM
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