General Information of the Compound
Compound ID
CP0537916
Compound Name
4-[(2R,3R,4R,5R)-3,4-bis(phenylmethoxy)-5-(phenylmethoxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-5-thione
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Structure
Formula
C28H29N3O4S
Molecular Weight
503.624
Canonical SMILES
S=c1[nH]ncn1[C@@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H]1OCc1ccccc1
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InChI
InChI=1S/C28H29N3O4S/c36-28-30-29-20-31(28)27-26(34-18-23-14-8-3-9-15-23)25(33-17-22-12-6-2-7-13-22)24(35-27)19-32-16-21-10-4-1-5-11-21/h1-15,20,24-27H,16-19H2,(H,30,36)/t24-,25-,26-,27-/m1/s1
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InChIKey
AHIORVJMAGWPGK-FPCALVHFSA-N
Physicochemical Property
logP
5.22569
Rotatable Bonds
11
Heavy Atom Count
36
Polar Areas
70.53
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 21797090
ChEMBL ID
CHEMBL3144354
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00819, 5-hydroxytryptamine receptor 1A
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000803 HA7 Homo sapiens (Human)  1
1
EC50 = 14.79 nM
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