General Information of the Compound
| Compound ID |
CP0537630
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| Compound Name |
US10266549, Example 208a
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| Structure |
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| Formula |
C15H12F3N5O
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| Molecular Weight |
335.289
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| Canonical SMILES |
FC(F)(F)c1cnc(Nc2ccc3ncoc3c2)nc1NC1CC1
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| InChI |
InChI=1S/C15H12F3N5O/c16-15(17,18)10-6-19-14(23-13(10)21-8-1-2-8)22-9-3-4-11-12(5-9)24-7-20-11/h3-8H,1-2H2,(H2,19,21,22,23)
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| InChIKey |
ZMGUVTBINPLWRA-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02366, Serine/threonine-protein kinase ULK1
Protein ID: PT01177, Serine/threonine-protein kinase ULK2